Best-practice guides (peer-reviewed reading list)#
Last reviewed: October 2026. Have a paper to add? Open an issue or use our submission form.
An annotated reading list of practical, mostly peer-reviewed guides for working with ABCD. If you only read one, start with Saragosa-Harris et al. (2022). Preprints are labeled as such.
Start here: practical & responsible-use guides#
Paper |
Why read it |
|---|---|
Saragosa-Harris, N. M., et al. (2022). A practical guide for researchers and reviewers using the ABCD Study and other large longitudinal datasets. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2022.101115 |
Written by trainees from the 2021 ABCD workshop. A checklist of analytic decisions, reproducibility, and equity considerations, useful for both authors and reviewers. |
Simmons, C., et al. (2021). Responsible use of open-access developmental data: The Adolescent Brain Cognitive Development (ABCD) Study. Psychological Science. doi:10.1177/09567976211003564 |
Ethical and interpretive pitfalls of open developmental data, from consortium members. |
Dick, A. S., et al. (2021). Meaningful associations in the Adolescent Brain Cognitive Development Study. NeuroImage. doi:10.1016/j.neuroimage.2021.118262 |
Effect sizes, covariate choice, weighting, and nesting in ABCD: how to interpret “small” effects. |
Owens, M. M., et al. (2021). Recalibrating expectations about effect size: A multi-method survey of effect sizes in the ABCD study. PLOS ONE. doi:10.1371/journal.pone.0257535 |
Benchmarks for typical (small) effect sizes across ABCD measures. |
Lopez, D. A., et al. (2024). Transparency and reproducibility in the Adolescent Brain Cognitive Development (ABCD) study. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2024.101408 |
Audit of 549 ABCD papers, with concrete recommendations for what to report. |
Study design, sampling, and weights#
Paper |
Why read it |
|---|---|
Volkow, N. D., et al. (2018). The conception of the ABCD study: From substance use to a broad NIH collaboration. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2017.10.002 |
Why the study exists and what it was designed to answer. |
Karcher, N. R., & Barch, D. M. (2020). The ABCD study: Understanding the development of risk for mental and physical health outcomes. Neuropsychopharmacology. doi:10.1038/s41386-020-0736-6 |
Overview of the study and early findings on mental and physical health risk. |
Garavan, H., et al. (2018). Recruiting the ABCD sample: Design considerations and procedures. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2018.04.004 |
School-based sampling, sites, and twins: the basis for modeling nesting and weights. |
Barch, D. M., et al. (2018). Demographic, physical and mental health assessments in the ABCD study. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2017.10.010 |
Rationale for the core non-imaging measures. |
Heeringa, S. G., & Berglund, P. A. (2020). A guide for population-based analysis of the ABCD Study baseline data. bioRxiv (preprint). doi:10.1101/2020.02.10.942011 |
How the ACS-raked propensity weights were built and when to use them. |
Gard, A. M., et al. (2023). Why weight? Analytic approaches for large-scale population neuroscience data. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2023.101196 |
Empirical comparison of weighted vs. unweighted ABCD analyses. |
Feldstein Ewing, S. W., et al. (2022). Measuring retention within the Adolescent Brain Cognitive Development (ABCD) study. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2022.101081 |
Who misses visits and why it matters for attrition bias. |
Longitudinal modeling and missing data#
Paper |
Why read it |
|---|---|
Hawes, S. W., et al. (2025). Longitudinal analysis of the ABCD® study. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2025.101518 |
ABCD-specific guide to longitudinal models. |
McCormick, E. M., et al. (2023). The Hitchhiker’s guide to longitudinal models: A primer on model selection for repeated-measures methods. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2023.101281 |
General primer on choosing a longitudinal model, with a code companion. |
King, K. M., et al. (2018). Longitudinal modeling in developmental neuroimaging research: Common challenges, and solutions from developmental psychology. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2017.11.009 |
Classic guide to the pitfalls of modeling change with brain data. |
Flournoy, J. C., et al. (2020). Improving practices and inferences in developmental cognitive neuroscience. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2020.100807 |
Concrete recommendations for inference in developmental neuroscience. |
Zacharek, S. J., et al. (2021). Leveraging big data to map neurodevelopmental trajectories in pediatric anxiety. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2021.100974 |
What large datasets like ABCD can and can’t tell us about developmental trajectories. |
Li, et al. (2025). Missing data approaches for longitudinal neuroimaging research: Examples from the ABCD Study®. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2025.101563 |
Alternatives to listwise deletion, demonstrated on ABCD. |
Thompson, W. K., et al. (2019). The structure of cognition in 9 and 10 year-old children and associations with problem behaviors: Findings from the ABCD study’s baseline neurocognitive battery. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2018.12.004 |
Worked example of mixed models with site and family random effects. |
Smith, D. M., et al. (2023). Heritability estimation of cognitive phenotypes in the ABCD Study® using mixed models. Behavior Genetics. doi:10.1007/s10519-023-10141-2 |
Modeling family relatedness (twins, siblings). |
For cross-lagged panel (RI-CLPM) and latent change score tutorials and code, see the Methods & open-science toolkit.
Neuroimaging#
Paper |
Why read it |
|---|---|
Casey, B. J., et al. (2018). The Adolescent Brain Cognitive Development (ABCD) study: Imaging acquisition across 21 sites. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2018.03.001 |
The MRI protocol and tasks. |
Hagler, D. J., Jr., et al. (2019). Image processing and analysis methods for the Adolescent Brain Cognitive Development Study. NeuroImage. doi:10.1016/j.neuroimage.2019.116091 |
The DAIRC pipeline behind the tabulated imaging measures. |
Feczko, E., et al. (2021). Adolescent Brain Cognitive Development (ABCD) Community MRI Collection and Utilities. bioRxiv (preprint). doi:10.1101/2021.07.09.451638 |
ABCD-BIDS and the community collection (ABCC). |
Parekh, P., et al. (2024). FEMA: Fast and efficient mixed-effects algorithm for large sample whole-brain imaging data. Human Brain Mapping. doi:10.1002/hbm.26579 |
The mixed-model engine behind DEAP analyses. |
Marek, S., et al. (2022). Reproducible brain-wide association studies require thousands of individuals. Nature. doi:10.1038/s41586-022-04492-9 |
Sample size and replicability for brain–behavior associations. |
Kennedy, J. T., et al. (2022). Reliability and stability challenges in ABCD task fMRI data. NeuroImage. doi:10.1016/j.neuroimage.2022.119046 |
Read before using task-fMRI measures as individual-difference variables. |
Elliott, M. L., et al. (2020). What is the test-retest reliability of common task-functional MRI measures? New empirical evidence and a meta-analysis. Psychological Science. doi:10.1177/0956797620916786 |
The broader evidence on task-fMRI reliability. |
Kragel, P. A., et al. (2020). fMRI can be highly reliable, but it depends on what you measure. PsyArXiv (preprint). doi:10.31234/osf.io/9eaxk |
A counterpoint: which fMRI measures are reliable. |
Chaarani, B., et al. (2021). Baseline brain function in the preadolescents of the ABCD Study. Nature Neuroscience. doi:10.1038/s41593-021-00867-9 |
Reference description of the baseline task-fMRI data. |
Klapwijk, E. T., et al. (2021). Opportunities for increased reproducibility and replicability of developmental neuroimaging. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2020.100902 |
Practical reproducibility steps for developmental imaging. |
Puberty#
Paper |
Why read it |
|---|---|
Cheng, T. W., et al. (2021). A researcher’s guide to the measurement and modeling of puberty in the ABCD Study® at baseline. Frontiers in Endocrinology. doi:10.3389/fendo.2021.608575 |
Practical guide to the puberty measures and how to model them. |
Herting, M. M., et al. (2021). Correspondence between perceived pubertal development and hormone levels in 9–10 year-olds from the ABCD Study. Frontiers in Endocrinology. doi:10.3389/fendo.2020.549928 |
How self/parent-report puberty relates to hormones. |
Multi-method assessment of pubertal timing and associations with internalizing psychopathology in early adolescent girls (PsyArXiv preprint, 2020) |
Comparing different ways to measure pubertal timing. |
Official documentation worth reading end-to-end#
ABCD release notes for your release