Best-practice guides (peer-reviewed reading list)#

Last reviewed: October 2026. Have a paper to add? Open an issue or use our submission form.

An annotated reading list of practical, mostly peer-reviewed guides for working with ABCD. If you only read one, start with Saragosa-Harris et al. (2022). Preprints are labeled as such.

Start here: practical & responsible-use guides#

Paper

Why read it

Saragosa-Harris, N. M., et al. (2022). A practical guide for researchers and reviewers using the ABCD Study and other large longitudinal datasets. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2022.101115

Written by trainees from the 2021 ABCD workshop. A checklist of analytic decisions, reproducibility, and equity considerations, useful for both authors and reviewers.

Simmons, C., et al. (2021). Responsible use of open-access developmental data: The Adolescent Brain Cognitive Development (ABCD) Study. Psychological Science. doi:10.1177/09567976211003564

Ethical and interpretive pitfalls of open developmental data, from consortium members.

Dick, A. S., et al. (2021). Meaningful associations in the Adolescent Brain Cognitive Development Study. NeuroImage. doi:10.1016/j.neuroimage.2021.118262

Effect sizes, covariate choice, weighting, and nesting in ABCD: how to interpret “small” effects.

Owens, M. M., et al. (2021). Recalibrating expectations about effect size: A multi-method survey of effect sizes in the ABCD study. PLOS ONE. doi:10.1371/journal.pone.0257535

Benchmarks for typical (small) effect sizes across ABCD measures.

Lopez, D. A., et al. (2024). Transparency and reproducibility in the Adolescent Brain Cognitive Development (ABCD) study. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2024.101408

Audit of 549 ABCD papers, with concrete recommendations for what to report.

Equity, race/ethnicity, and social context#

Paper

Why read it

Cardenas-Iniguez, C., & Gonzalez, M. R. (2024). Recommendations for the responsible use and communication of race and ethnicity in neuroimaging research. Nature Neuroscience. doi:10.1038/s41593-024-01608-4

How (and whether) to include race/ethnicity variables, and how to write about them.

Gonzalez, M. R., et al. (2025). Responsible research in health disparities using the ABCD study. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2024.101497

Social-determinants-of-health framework for disparities research in ABCD.

Further reading on race, racism, and social determinants of health:

Study design, sampling, and weights#

Paper

Why read it

Volkow, N. D., et al. (2018). The conception of the ABCD study: From substance use to a broad NIH collaboration. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2017.10.002

Why the study exists and what it was designed to answer.

Karcher, N. R., & Barch, D. M. (2020). The ABCD study: Understanding the development of risk for mental and physical health outcomes. Neuropsychopharmacology. doi:10.1038/s41386-020-0736-6

Overview of the study and early findings on mental and physical health risk.

Garavan, H., et al. (2018). Recruiting the ABCD sample: Design considerations and procedures. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2018.04.004

School-based sampling, sites, and twins: the basis for modeling nesting and weights.

Barch, D. M., et al. (2018). Demographic, physical and mental health assessments in the ABCD study. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2017.10.010

Rationale for the core non-imaging measures.

Heeringa, S. G., & Berglund, P. A. (2020). A guide for population-based analysis of the ABCD Study baseline data. bioRxiv (preprint). doi:10.1101/2020.02.10.942011

How the ACS-raked propensity weights were built and when to use them.

Gard, A. M., et al. (2023). Why weight? Analytic approaches for large-scale population neuroscience data. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2023.101196

Empirical comparison of weighted vs. unweighted ABCD analyses.

Feldstein Ewing, S. W., et al. (2022). Measuring retention within the Adolescent Brain Cognitive Development (ABCD) study. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2022.101081

Who misses visits and why it matters for attrition bias.

Longitudinal modeling and missing data#

Paper

Why read it

Hawes, S. W., et al. (2025). Longitudinal analysis of the ABCD® study. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2025.101518

ABCD-specific guide to longitudinal models.

McCormick, E. M., et al. (2023). The Hitchhiker’s guide to longitudinal models: A primer on model selection for repeated-measures methods. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2023.101281

General primer on choosing a longitudinal model, with a code companion.

King, K. M., et al. (2018). Longitudinal modeling in developmental neuroimaging research: Common challenges, and solutions from developmental psychology. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2017.11.009

Classic guide to the pitfalls of modeling change with brain data.

Flournoy, J. C., et al. (2020). Improving practices and inferences in developmental cognitive neuroscience. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2020.100807

Concrete recommendations for inference in developmental neuroscience.

Zacharek, S. J., et al. (2021). Leveraging big data to map neurodevelopmental trajectories in pediatric anxiety. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2021.100974

What large datasets like ABCD can and can’t tell us about developmental trajectories.

Li, et al. (2025). Missing data approaches for longitudinal neuroimaging research: Examples from the ABCD Study®. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2025.101563

Alternatives to listwise deletion, demonstrated on ABCD.

Thompson, W. K., et al. (2019). The structure of cognition in 9 and 10 year-old children and associations with problem behaviors: Findings from the ABCD study’s baseline neurocognitive battery. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2018.12.004

Worked example of mixed models with site and family random effects.

Smith, D. M., et al. (2023). Heritability estimation of cognitive phenotypes in the ABCD Study® using mixed models. Behavior Genetics. doi:10.1007/s10519-023-10141-2

Modeling family relatedness (twins, siblings).

For cross-lagged panel (RI-CLPM) and latent change score tutorials and code, see the Methods & open-science toolkit.

Neuroimaging#

Paper

Why read it

Casey, B. J., et al. (2018). The Adolescent Brain Cognitive Development (ABCD) study: Imaging acquisition across 21 sites. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2018.03.001

The MRI protocol and tasks.

Hagler, D. J., Jr., et al. (2019). Image processing and analysis methods for the Adolescent Brain Cognitive Development Study. NeuroImage. doi:10.1016/j.neuroimage.2019.116091

The DAIRC pipeline behind the tabulated imaging measures.

Feczko, E., et al. (2021). Adolescent Brain Cognitive Development (ABCD) Community MRI Collection and Utilities. bioRxiv (preprint). doi:10.1101/2021.07.09.451638

ABCD-BIDS and the community collection (ABCC).

Parekh, P., et al. (2024). FEMA: Fast and efficient mixed-effects algorithm for large sample whole-brain imaging data. Human Brain Mapping. doi:10.1002/hbm.26579

The mixed-model engine behind DEAP analyses.

Marek, S., et al. (2022). Reproducible brain-wide association studies require thousands of individuals. Nature. doi:10.1038/s41586-022-04492-9

Sample size and replicability for brain–behavior associations.

Kennedy, J. T., et al. (2022). Reliability and stability challenges in ABCD task fMRI data. NeuroImage. doi:10.1016/j.neuroimage.2022.119046

Read before using task-fMRI measures as individual-difference variables.

Elliott, M. L., et al. (2020). What is the test-retest reliability of common task-functional MRI measures? New empirical evidence and a meta-analysis. Psychological Science. doi:10.1177/0956797620916786

The broader evidence on task-fMRI reliability.

Kragel, P. A., et al. (2020). fMRI can be highly reliable, but it depends on what you measure. PsyArXiv (preprint). doi:10.31234/osf.io/9eaxk

A counterpoint: which fMRI measures are reliable.

Chaarani, B., et al. (2021). Baseline brain function in the preadolescents of the ABCD Study. Nature Neuroscience. doi:10.1038/s41593-021-00867-9

Reference description of the baseline task-fMRI data.

Klapwijk, E. T., et al. (2021). Opportunities for increased reproducibility and replicability of developmental neuroimaging. Developmental Cognitive Neuroscience. doi:10.1016/j.dcn.2020.100902

Practical reproducibility steps for developmental imaging.

Puberty#

Paper

Why read it

Cheng, T. W., et al. (2021). A researcher’s guide to the measurement and modeling of puberty in the ABCD Study® at baseline. Frontiers in Endocrinology. doi:10.3389/fendo.2021.608575

Practical guide to the puberty measures and how to model them.

Herting, M. M., et al. (2021). Correspondence between perceived pubertal development and hormone levels in 9–10 year-olds from the ABCD Study. Frontiers in Endocrinology. doi:10.3389/fendo.2020.549928

How self/parent-report puberty relates to hormones.

Multi-method assessment of pubertal timing and associations with internalizing psychopathology in early adolescent girls (PsyArXiv preprint, 2020)

Comparing different ways to measure pubertal timing.

Official documentation worth reading end-to-end#